Common Side Effects
Common Side effect ' feature some impressive starring operation from two actors who do n’t usually get to take the limelight . The Adult Swim / Max animated seriesCommon Side Effectsis an off - pulsation but cutting irony of forward-looking medicine and regime , enfold up in a morally - driven conspiracy caper . After discovering a likely curative - all that could save countless lifetime across the world , fungi expert and universal oddball Marshall Cuso finds himself on the footrace from the party and government who want to keep his knowledge a secret .
bolster by solid brio , an impressive voice mold , and heady concepts that go beyond the typical limit of modernistic animated shows , Common Side Effectshas been one of the best shows to debut so far in 2025 . While the voice shape does let in some fabled figure from animation , the fundamental part of Marshall is played by someone more well be intimate for their oeuvre behind the scenes than in front of the camera . Here isthe throw up ofCommon Side Effects , who they play , and where you ’ve seen their work before .
Dave King As Marshall Cuso
Born June 6, 1978
Active Since:2002
Actor : Marshall Cuso stars inCommon Side Effectsas Dave King , the key role of the liven series . Dave King has been forge in television for class , but chiefly behind the scenes as a author and producer instead of an actor . Getting his start onCrank YankersandLast Call With Carson Daly , King become on to publish for shows likeWorkaholics , The Simpsons , Parks and Recreation , andEnglish Teacher . He has seem in many of those display as a nonaged character . Common Side Effectsis his first voice - over role , as well as his first starring role in a show .
celebrated tv set Shows Dave King Has Written For
Notable episode
Parks and Recreation
" Citizen Knope , " " Two company "
Custom Image by Yailin Chacon
The Good Place
" service Is Other People "
English Teacher
" Field Trip , " " Convention "
Character : Marshall Cuso is the lead character ofCommon Side Effects , a well - stand for expert on fungai who find himself on the running . After discovering a mysterious Modern melodic phrase of mushroom-shaped cloud known as the Blue Angel that can mend any and all illness or injury , Marshall risks his life to bring the potential cure - all to his former high school friend Frances . Marshall isCommon Side Effects ' main Hero of Alexandria , even as the show shift key focus to other more morally compromised role like Frances .
Emily Pendergast As Frances Applewhite
Born February 25, 1987
Active Since:2013
histrion : Emily Pendergast stars inCommon Side Effectas Frances Applewhite . abide in Youngstown , Ohio , Pendergast got her starting time in unforesightful films before do the move to idiot box . Pendergast found her breakout role in season 7 ofVeep , where she bring Beth , the wife ( and half - sister ) of United States President Jonah Ryan . She has since appeared in several films likeDescendent , shows likeWe’re Doing Good , and podcasts likeMeet Cute .
Notable Emily Pendergast Films & TV Shows
function
Veep
Beth
We ’re Doing Good
Nora
LaRoy , Texas
Kayla
Character : Frances Applewhite is the junior-grade agonist ofCommon Side Effects . A former friend and class fellow of Marshall , Frances went down a different path and find oneself herself working as an executive assistant for Reutical Pharmaceuticals , which seeks to stamp out any knowledge about the Blue Angel before it reaches the public . While Marshall is the driving force ofCommon Side Effects , Jacques Anatole Francois Thibault ' attempts to wrestle with her own dream and sense of morality is the show ’s thematic core .
Mike Judge As Rick Kruger
Born October 17, 1962
Active Since:1991
thespian : Mike Judge is one of the stars ofCommon Side Effects , as well as an executive manufacturer on the show . carry in Guayaquil , Ecuador and raised in New Mexico , Judge ’s short filmFrog Baseballintroduced the fictional character of Beavis and Butt - head , who were spin - off into a show for MTV.The breakout achiever ofBeavis and Butt - headled to the development of critically acclaimed shows likeKing of the Hilland picture likeOffice Space . evaluator voices fictional character in bothBeavis and Butt - headandKing of the Hill , and bring those talents toCommon Side Effectsas Rick Kruger .
Notable Mike Judge Films / TV Shows
Beavis & Butthead
Maker , Beavis , Butt - Head , David Van Driessen , Tom Anderson , extra vocalism
King of the Hill
Creator , Hank Hill , Jeff Boomhauer , Stuart Dooley , additional voices
Idiocracy
Director , Writer , Producer , I.Q trial run political machine
theatrical role : Rick Kruger is a higher - up at Reutical Pharmaceuticals , as well as Frances ' direct supervisor at the federal agency . Initially lay out as an aloof and careless executive at the company , the unveiling of Blue Angel terminate up get a change in him . As the show come on , Rick becomes a astonishingly reflective characterafter he learns the reliable potential of the mushroom — as well as the distance Reutical will go to keep it hidden from the public .
Common Side Effects Supporting Cast & Characters
Common Side Effects Has A Supporting Cast Full Of Seasoned Character Actors
Common Side Effectshas a fairly large supporting cast of characterswho flesh out the setting and the personal lives of the characters with some impressive supporting player . Joseph Lee Anderson ( Young Rock ) and Martha Kelly ( Baskets ) play DEA Agents Copano and Harrington severally , who find themselves investigating Marshall and becoming entangled in the conspiracy to keep Blue Angel mystery . Frances ' indolent young man Nick is play by Ben Feldman ( Superstore ) , while her dementia - afflicted mother Sonia is played by Lin Shaye ( A Nightmare On Elm Street ) .
Common Side Effects is one of the most exciting show coming out of Adult Swim in 2025 , and the creators hash out the story with Screen Rant at SCAD .
Danny Huston ( Yellowstone ) serve up as theCommon Side Effects ' central overarching antagonist , Reutical board member Jonas Backstein , while Christine Ko ( Dave ) plays Kiki , a research worker at Reutical that furnish favourable findings for the company . The most enigmatic character in the show is Hildy , Marshall ’s former wise man who wants the Blue Angel for her own end . Hildy is vocalize by vivification legend Sue Rose ( Pepper Ann).Common Side Effectshas an impressive mould , serving as a swell vitrine for some talent that ’s rarely train center - stage in show .
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