A.P. Bio

The former NBC sitcomA.P. Biohas a robust cast full of screaming main and supporting characters . Mike O’Brien ofSaturday Night Liveacclaim created the original sitcom , which first premier on February 1 , 2018 . The show is focus around prof turned high - school teacher Jack Griffin , who is played byGlenn Howerton ofIt ’s Always Sunny in Philadelphia . A.P. Biofollows Jack as he transition from being a philosophy professor at Harvard University to an A.P. Biology teacher at his hometown high school after fall from state of grace due to a YouTube TV .

A.P. Bioran for two season on NBC before moving to Peacockfor its final two seasons . The series was delete twiceeven though itmaintained an impressive Rotten Tomatoesscore of 88 % , with its second and third seasons earning thoroughgoing 100 % critic scores . Despite the positive reviews of A.P. Bio , there was not enough coherent viewership for the series to continue past four seasons . Over its four - year span , A.P. Biofeatured several noteworthy guest stars and cameo appearance , making it one of the most ungratifying sitcoms in recent retentivity .

A.P. Bioseasons 1 - 4 are useable to stream on Netflix and Peacock .

a.p.bio

Glenn Howerton as Jack Griffin

Actor : Glenn Howerton , 48 , is an American actor who was behave in Japan . He is considerably fuck for playing Dennis Reynolds on the come to FX funniness seriesIt ’s Always Sunny In Philadelphia , which is the longest - range original comedy serial in television account . Howeton co - create the serial with co - star Rob McElhenney . Howerton made his film first appearance with 2005’sMust Love Dogsand has also appeared in films such asCrank , The Strangers , Everything Must Go , The Hunt , andBlackberry . Howerton ’s other noted performances in telly includeThat ' 80s Show(2002),The Mindy Project(2012–2017),Fargo(2014 ) , andVelma(2023 - 2024 ) .

Notable Works :

Film / Series

A composite image of characters from AP Bio

Custom Image by Yeider Chacon

grapheme

It ’s Always Sunny In Philadelphia

Dennis Reynolds

Stef wears a pink blouse on A.P. Bio

A.P. Bio is an NBC comedy that premiered in 2018. The sitcom stars It’s Always Sunny in Philidelphia’s Glenn Howerton as Jack Griffin, a former philosophy professor who starts working as a high school advanced placement biology teacher. After season 2, A.P. Bio moved to Peacock for two seasons before getting canceled in 2021.

Fargo

Don Chumph

blackberry bush

Mary Wagner laughing with Principal Durbin

Jim Balsillie

Character : Howerton hotshot as the main character Dr. Jack Griffin inA.P. Bio .

Lyric Lewis as Stef Duncan

Actor : Lyric Lewis , 39 , is an American actress and writer from New Orleans , Louisiana . Lewis is best do it forWaffles + Mochi , Mad TV , and the Dreamworks seriesCurses!on Apple TV+ . She has made guest appearances on several notable comedy series and situation comedy , including but not bound toBrooklyn Nine - Nine , Baskets , iCarly , Party Down , andNight Court . She has also made several appearances as herself on television shows such asDrunk account , Is It Cake ? , andThe Wheel . Lewis is expect to star in the approaching myopic filmI Am a Gigantosaurus , Actuallyalongside Alison Brie .

Waffles + Mochi

Chef

Michelle Jones sitting at desk on A.P. Bio

Curses !

flip

Baskets

mapleworth murders paula pell

Monica

Character : Lewis star as the account instructor Stef Duncan inA.P. Bio .

Mary Sohn as Mary Wagner

histrion : Mary Sohn , 44 , is an American actress from Illinois . Sohn is best known for her purpose inThe Boss , Between Two Ferns : The Movie , Love , Grace and Frankie , andComedy Bang ! Bang ! . She recently appeared in an episode ofCurb Your Enthusiasmand in the TBS seriesMiracle Workers . She lift to prominence after Edgar Albert Guest star in an episode of the notable HBO comedy seriesHello Ladiesin 2013 . She has also guest starred in episode ofTeachers , Superior Donuts , Shrink , andBajillion Dollar Propertie$.

Between Two Ferns : The Movie

Tina

A.P. Bio - Season 2

restrict Your ebullience

Waitress

Hello Ladies

Headshot Of Glenn Howerton

Barbara

fictitious character : Sohn play the art teacher Mary Wagner inA.P. Bio .

Jean Villepique as Michelle Jones

histrion : Jean Villepique is an American actress from New Jersey who attended Northwestern University . As a former member of The Second City , she is best roll in the hay for her roles inBoJack HorsemanandUp All Night . She made her tv debut in 2007 in installment of30 RockandCurb Your Enthusiasm . She also starred alongside Jason Segel and Paul Rudd in the 2009 comedyI Love You , Man . She has invitee starred in many illustrious comedy serial such asModern Family , Workaholics , Grey ’s Anatomy , Baskets , New Girl , andBetter Call Saul . She is also make love for playing Gretchen inSharp Objects .

I Love You , Man

Leanne

A.P. Bio

Better Call Saul

Doreen Valco

astute object

Gretchen

Character : Villepique plays home ec teacher Michelle Jones inA.P. Bio .

Paula Pell as Helen Henry Demarcus

Actor : Paula Pell , 61 , is an American comedy author , producer , and actress from Illinois . Pell is a prolific writer forSaturday Night Livewho has writing credits for more than 315SNLepisodes between 1995 and the present daytime . As an actress , Pell has appear inParks and Recreation,30 Rock , Anchorman 2,Inside Out , The Mindy Project , Unbreakable Kimmy Schmidt , andInside Out 2 . She also voiced various roles in the Netflix animated seriesBig Mouth . She is slat to star alongside Matt Berry , Bill Hader , and Quinta Bronson in the upcomingThe Cat in the Hatfilm as well asSummer of 69with Chloe Fineman , Charlie Day , and Natalie Morales .

Saturday Night Live

Various

Inside Out

Big Mouth

fiber : Pell play schooltime administrator Helen Henry Demarcus inA.P. Bio .

Patton Oswalt as Principal Ralph Durbin

Actor : Patton Oswalt , 55 , is an American comedian and actor from Virginia who has more than 250 professional playing credits to his name . He is best known for his roles inRatatouille , Young Adult , The Secret Life of Walter Mitty , andSeeking a Friend for the destruction of the World . He has recently appeared inHacks , Manhunt , Ghostbusters : Frozen Empire , Family Guy , What We Do in the Shadows , and80 for Brady . He is also an award - winning stand - up comic who has been nominated for 4 Emmys with one win for Outstanding Writing for a Variety Special for 2016’sTalking for Clapping .

Ratatouille

Remy

The Secret Life of Walter Mitty

Todd

Hacks

Himself

fictional character : Oswalt play Principal Ralph Durbin inA.P. Bio .

A.P. Bio Supporting Cast & Characters

Aparna Brielle as Sarika : Brielle is well known forFUBARandMech Cadets .

Nick Peine as Marcus : Peine is best known forOffice Christmas PartyandJust Getting Started .

Allisyn Snyder as Heather : Snyder is well known forAstrid CloverandMeet Dave .

Eddie Leavy as Anthony : Leavy is best known forBest . World . Weekend . Ever.andThose Who Ca n’t .

Jacob Houston as Victor : Houston is best know forYellowjacketsandL.A. ’s Finest .

Sari Arambulo as Grace : Arambulo is best know forAlexa & KatieandParty of Five .

Spence Moore II as Dan Decker : Moore is best known forCreed IIIandWe Are Who We Are .

Marisa Baram as Marissa : Baram is well lie with forHenry DangerandReal Husbands of Hollywood .

Miguel Lee as Eduardo : Lee is best known forDaveandThe Saver .

Charlie McCrackin as Coach Dick Novak : McCracking is best known forIntergalactic RadioandUnstable .

A.P. Bio Cameo Guide

Nikki Glaser as Chloe from Baltimore : Glaser is best known forTrainwreckandThe Roast of Tom Brady .

Niecy Nash as Kim Burke : Nash is best lie with forReno 911!andGuess Who .

Taran Killam as Mr. Vining : Killam is best known forSaturday Night Liveand12 Years a striver .

Mark Proksch as Philip : Proksch is best bang forBetter Call SaulandWhat We Do in the Shadows .

Jon Lovitz as Robin Schwonk : Lovitz is best known forA League of Their OwnandRat Race .

Ron Funches as Hans : Funches is best known forTrollsandInside Out 2 .

Angela Kinsey as Brenda : Kinsey is well bed forThe Officeand has a cameo inA.P. Bio .

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Cast

A.P. Bio is an NBC comedy that premiered in 2018 . The sitcom stars It ’s Always Sunny in Philidelphia ’s Glenn Howerton as Jack Griffin , a former philosophy prof who starts work as a gamey school sophisticated position biology teacher . After time of year 2 , A.P. Bio run to Peacock for two season before getting canceled in 2021 .